| Date | Time | W/L | Opp. |
| Preseason | |||
| Thu 8/12/2010 | 27-24 | W | vs Saints |
| Thu 8/19/2010 | 28-10 | W | @ Falcons |
| Thu 8/26/2010 | 36-35 | L | vs Rams |
| Thu 9/2/2010 | 20-17 | L | @ Giants |
| Reg. Season | |||
| Sun 9/12/2010 | 1:00 PM | vs Bengals | |
| Sun 9/19/2010 | 4:15 PM | @ Jets | |
| Sun 9/26/2010 | 1:00 PM | vs Bills | |
| Mon 10/4/2010 | 8:30 PM | @ Dolphins | |
| Sun 10/10/2010 | Bye | ||
| Sun 10/17/2010 | 1:00 PM | vs Ravens | |
| Sun 10/24/2010 | 4:15 PM | @ Chargers | |
| Sun 10/31/2010 | 4:15 PM | vs Vikings | |
| Sun 11/7/2010 | 1:00 PM | @ Browns | |
| Sun 11/14/2010 | 8:20 PM | @ Steelers | |
| Sun 11/21/2010 | 4:15 PM | vs Colts | |
| Thu 11/25/2010 | 12:30 PM | @ Lions | |
| Mon 12/6/2010 | 8:30 PM | vs Jets | |
| Sun 12/12/2010 | 1:00 PM | @ Bears | |
| Sun 12/19/2010 | 8:20 PM | vs Packers | |
| Sun 12/26/2010 | 1:00 PM | @ Bills | |
| Sun 1/2/2011 | 1:00 PM | vs Dolphins | |